Molecular basis of cell differentiation and Cellular Therapy
mESC
indiferenciada
mESC
diferenciada
Coloração com
Ditizona
Murine embryonic stem cells (MESC) undifferentiated, differentiated into insulin-producing cells (IPCs) and differentiated into insulin-producing cells labeled for insulin (Dithizone: red)
Obejectives
Identify genes and proteins differentially expressed during the differentiation of stem cells in bone (osteogenesis), skin and pancreatic beta cells produce insulin. The goal is to get differentiated cells and tissues with the aim of cell therapy and tissue engineering.
Projects in development
- Stem cells and senescence;
- Osteogenesis and chondrogenesis;
- Differentiation of stem cells into beta-cells producing insulin
- Pancreatic islet encapsulation.
Sectors of application
- Public health care;
- College education.