Generation of cell lines producing recombinant protein of therapeutic and biotechnological interest
Insect Cell
BEVS
Mammalian
Cells
Bacteria
Prolactin
BMPS
Leptin
FSH
FVIII, FIX, FvW
PDGF-BB
TGF-Beta 1,3
G-CSG
GM-CSF
VEGF
Amylin
LIFs
FGF2
Produced biopharmaceuticals and cell lines used.
Objectives
Produce recombinant proteins in different heterologous expression systems (bacteria, baculovirus/insect cells (BEVs) and mammalian cells) in order to Molecular Therapy of human and animal diseases and tissue engineering both bone and soft
Projects in development
- Human coagulation factors establishing (FVIII, FIX, vW);
- Establishing of peptide growth/differentiation factors (PDGF-BB, TGF-B, VEGF, BMPs, RSPO1);
- Production of recombinant peptide hormones (PRL, Amylin, Leptin, FSH, eCG);
- Heterologus expression using Bacterial Systems, BEVs and Mammalian Cells
Sectors of Application
- People health care;
- Livestock, veterinary services inclusive;
- Products and biotechnological processes related to human or animal health.